Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

31 Jan 2018

Abstract excerpt

Previous studies have shown that mouse dermis is composed of functionally distinct fibroblast lineages. To explore the extent of fibroblast heterogeneity in human skin, we used a combination of comparative spatial transcriptional profiling of human and mouse dermis and single-cell transcriptional profiling of human dermal fibroblasts. We show that there are at least four distinct fibroblast populations in adult...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Skin and Cellular Biology Research
Share to Skin Protection and Aging
Share to Wound Healing and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29391249
DOI: 10.1016/j.jid.2018.01.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast SubpopulationsPMID 29391249Read ↗

Understanding the impact of fibroblast heterogeneity on skin fibrosis.Semantic proximity Read ↗

Diversity, topographic differentiation, and positional memory in human fibroblasts.Semantic proximity Read ↗

Understanding Fibroblast Heterogeneity in Form and FunctionSemantic proximity Read ↗

Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease.Semantic proximity Read ↗

A single cell and spatial genomics atlas of human skin fibroblasts in health and diseaseSemantic proximity Read ↗

Skin fibroblast functional heterogeneity in health and diseaseSemantic proximity Read ↗

Markers of Dermal Fibroblast Subpopulations for Viable Cell Isolation via Cell Sorting: A Comprehensive ReviewSemantic proximity Read ↗

Integrated spatial multiomics reveals fibroblast fate during tissue repairSemantic proximity Read ↗

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming.Semantic proximity Read ↗

Origin and functional heterogeneity of fibroblastsSemantic proximity Read ↗

Identification, discrimination and heterogeneity of fibroblastsSemantic proximity Read ↗

Deciphering the functional heterogeneity of skin fibroblasts using single‐cell RNA sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.