Article
Diversity, topographic differentiation, and positional memory in human fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002
Chang Howard Y, Chi Jen-Tsan, Dudoit Sandrine, Bondre Chanda, van de Rijn Matt, Botstein David, Brown Patrick O
Abstract excerpt
A fundamental feature of the architecture and functional design of vertebrate animals is a stroma, composed of extracellular matrix and mesenchymal cells, which provides a structural scaffold and conduit for blood and lymphatic vessels, nerves, and leukocytes. Reciprocal interactions between mesenchymal and epithelial cells are known to play a critical role in orchestrating the development and morphogenesis of...
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