Article
Automated cell cycle and cell size measurements for single-cell gene expression studies.
BMC research notes - 1 Feb 2018
Guillemin Anissa, Richard Angélique, Gonin-Giraud Sandrine, Gandrillon Olivier
Abstract excerpt
OBJECTIVES: Recent rise of single-cell studies revealed the importance of understanding the role of cell-to-cell variability, especially at the transcriptomic level. One of the numerous sources of cell-to-cell variation in gene expression is the heterogeneity in cell proliferation state. In order to identify how cell cycle and cell size influences gene expression variability at the single-cell level, we provide...
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