Article
Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies.
Genetic epidemiology - 1 Feb 2013
Walsh Kyle M, Anderson Erik, Hansen Helen M, Decker Paul A, Kosel Matt L, Kollmeyer Thomas, Rice Terri, Zheng Shichun, Xiao Yuanyuan, Chang Jeffrey S, McCoy Lucie S, Bracci Paige M, Wiemels Joe L, Pico Alexander R, Smirnov Ivan, Lachance Daniel H, Sicotte Hugues, Eckel-Passow Jeanette E, Wiencke John K, Jenkins Robert B, Wrensch Margaret R
Abstract excerpt
Genomewide association studies (GWAS) and candidate-gene studies have implicated single-nucleotide polymorphisms (SNPs) in at least 45 different genes as putative glioma risk factors. Attempts to validate these associations have yielded variable results and few genetic risk factors have been cons...
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