Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A Viewpoint

23 Jan 2018

Abstract excerpt

Iron is essential for cellular development and maintenance of multiple physiological processes in the central nervous system. The disturbance of its homeostasis leads to abnormal iron deposition in the brain and causes neurotoxicity via generation of free radicals and oxidative stress. Iron toxicity has been established in the pathogenesis of Parkinson's disease; however, its contribution to multiple system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29376857
DOI: 10.3233/jad-170601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A ViewpointPMID 29376857Read ↗

Regional and cellular iron deposition patterns predict clinical subtypes of multiple system atrophySemantic proximity Read ↗

Understanding the pathogenesis of multiple system atrophy: state of the art and future perspectivesSemantic proximity Read ↗

The roles of iron and HFE genotype in neurological diseases.Semantic proximity Read ↗

Brain Iron Metabolism and Neurodegenerative DisordersSemantic proximity Read ↗

Iron dysregulation and neurodegeneration: the molecular connection.Semantic proximity Read ↗

The relevance of iron in the pathogenesis of Parkinson’s diseaseSemantic proximity Read ↗

Alpha-synuclein: relating metals to structure, function and inhibition.Semantic proximity Read ↗

Multiple System Atrophy: Pathology, Pathogenesis, and Path ForwardSemantic proximity Read ↗

Understanding the Mechanism of Ferroptosis in Neurodegenerative DiseasesSemantic proximity Read ↗

Ferroptosis and Iron Homeostasis: Molecular Mechanisms and Neurodegenerative Disease ImplicationsSemantic proximity Read ↗

Neurodegeneration with Brain Iron Accumulation Disorders: Valuable Models Aimed at Understanding the Pathogenesis of Iron DepositionSemantic proximity Read ↗

Heterogeneity of Multiple System Atrophy: An UpdateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.