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Article

The roles of iron and HFE genotype in neurological diseases.

Molecular aspects of medicine - 1 Oct 2020

Kim Yunsung, Connor James R

Abstract excerpt

Iron accumulation is a recurring pathological phenomenon in many neurological diseases including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, and others. Iron is essential for normal development and functions of the brain; however, excess redox-active iron can also lead to oxidative damage and cell death. Especially for terminally differentiated cells like neurons, regulation of...

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PMID: 32654761
DOI: 10.1016/j.mam.2020.100867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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