Article
Iron dysregulation and neurodegeneration: the molecular connection.
Molecular interventions - 1 Apr 2006
Lee Donna W, Andersen Julie K, Kaur Deepinder
Abstract excerpt
Iron is essential for many biological processes however excess concentrations can be harmful to many tissues. Its amounts must therefore be carefully regulated in all cells of the body including those in the brain. Increased amounts of iron have been reported in many neurodegenerative disorders. Whether this increased iron contributes to neurodegeneration has been considered controversial. In this review, we...
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