Article
Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Annals of the rheumatic diseases - 1 Apr 2018
Ortiz-Fernández Lourdes, Carmona Francisco David, López-Mejías Raquel, González-Escribano Maria Francisca, Lyons Paul A, Morgan Ann W, Sawalha Amr H, Merkel Peter A, Smith Kenneth G C, González-Gay Miguel A, Martín Javier
Abstract excerpt
OBJETIVE: Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis. METHODS: Immunochip genotyping data from 2465 patients diagnosed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.