Article
Analysis of CDK2 mutations in Chinese men with non-obstructive azoospermia who underwent testis biopsy.
Reproductive biomedicine online - 1 Mar 2018
Liu Wen, Gao Xuan, Yan Lei, Liu Hongli, Yu Ruimei, Zhao Shidou, Ma Jinlong
Abstract excerpt
To examine whether mutations of the CDK2 gene exist in Chinese men with non-obstructive azoospermia (NOA) with different histopathology, we recruited 175 Chinese men with idiopathic NOA who underwent testis biopsy, including hypospermatogenesis, germ cell maturation arrest and Sertoli cell only syndrome. Genomic DNA was extracted from peripheral blood samples. Subsequently, the seven exons of the CDK2 gene were...
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