Article
Replication study and meta-analysis of human nonobstructive azoospermia in Japanese populations.
Biology of reproduction - 1 Apr 2013
Sato Youichi, Jinam Timothy, Iwamoto Teruaki, Yamauchi Aiko, Imoto Issei, Inoue Ituro, Tajima Atsushi
Abstract excerpt
Recently, a Chinese genomewide association study (GWAS) identified four autosomal single-nucleotide polymorphism (SNP) loci as being significantly associated with risk factors for nonobstructive azoospermia (NOA; P < 5 × 10(-8)). In the present study, we performed a replication study on two Japanese cohorts from different institutions in order to evaluate whether SNP loci are associated with NOA. The four SNPs...
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