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Article

The TNP1 haplotype - GCG is associated with azoospermia.

International journal of andrology - 1 Apr 2011

Khattri A, Bhushan S S, Sireesha V, Gupta N J, Chakravarty B N, Deendayal M, Prasad S, Singh L, Thangaraj K

Abstract excerpt

Transition nuclear proteins (TNP1 and TNP2) are the major nuclear proteins that replace somatic histones during spermatogenesis. TNPs are required for the maintenance of normal spermatogenesis. Moreover, spermatogenesis was found to be compromised in both Tnp1 and Tnp2 null mice. As no study is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Infertility, Male

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 20522125
DOI: 10.1111/j.1365-2605.2010.01072.x

Genes

TNP1
TNP2
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20522125-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

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The TNP1 haplotype - GCG is associated with azoospermia.PMID 20522125Read ↗

Common genetic variation in KATNAL1 non-coding regions is involved in the susceptibility to severe phenotypes of male infertility.Semantic proximity Read ↗

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