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Article

Analysis of STAG3 variants in Chinese non-obstructive azoospermia patients with germ cell maturation arrest.

Scientific reports - 12 May 2021

Liu Wen, Gao Xuan, Zhang Haobo, Liu Ran, Cao Yongzhi, Yu Ruimei, Fang Ge, Ma Jinlong, Zhao Shidou

Abstract excerpt

STAG3 is essential for male meiosis and testis of male Stag3-/- mice shows the histopathological type of germ cell maturation arrest (MA). Whether variants of the STAG3 gene exist in Chinese idiopathic non-obstructive azoospermia (NOA) patients needs to be determined. We recruited 58 Chinese NOA men with MA who underwent testis biopsy and 192 fertile men as the control group. The 34 exons of the STAG3 gene were...

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Identifiers

PMID: 33980954
DOI: 10.1038/s41598-021-89559-9
PMCID: PMC8115624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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