Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of the GATA4 gene in Chinese men with nonobstructive azoospermia.

Asian journal of andrology - 1 Jan 2000

Zhang Xu, Zhang Tai-Jian, Liu Wen, Ning Yun-Na, Bian Yue-Hong, Cao Yong-Zhi, Liu Hong-Bin, Ma Jin-Long, Zhang Hao-Bo

Abstract excerpt

As a crucial transcription factor for spermatogenesis, GATA-binding protein 4 (GATA4) plays important roles in the functioning of Sertoli and Leydig cells. Conditional knockout of GATA4 in mice results in age-dependent testicular atrophy and loss of fertility. However, whether GATA4 is associated with human azoospermia has not been reported. Herein, we analyzed the GATA4 gene by direct sequencing of samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Azoospermia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Claudins

Share to GATA4 Transcription Factor

Share to Mutation, Missense

Share to Phosphoproteins

Share to Steroidogenic Acute Regulatory Protein

Share to Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 32859868
DOI: 10.4103/aja.aja_33_20
PMCID: PMC7991814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the GATA4 gene in Chinese men with nonobstructive azoospermia.PMID 32859868Read ↗

Analysis of TATA-box binding protein associated factor 4b gene mutations in a Chinese population with nonobstructive azoospermia.Semantic proximity Read ↗

Identification of risk genes in Chinese nonobstructive azoospermia patients based on whole-exome sequencing.Semantic proximity Read ↗

The PGAM4 gene in non-obstructive azoospermia.Semantic proximity Read ↗

Targeted Next-Generation Sequencing Identifies Novel Sequence Variations of Genes Associated with Nonobstructive Azoospermia in the Han Population of Northeast ChinaSemantic proximity Read ↗

MBOAT1 homozygous missense variant causes nonobstructive azoospermia.Semantic proximity Read ↗

CREM variants rs4934540 and rs2295415 conferred susceptibility to nonobstructive azoospermia risk in the Chinese population.Semantic proximity Read ↗

Mutations in SOHLH1 gene associate with nonobstructive azoospermia.Semantic proximity Read ↗

Loss-of-function mutation in GATA4 causes anomalies of human testicular development.Semantic proximity Read ↗

GATA4 Single-Amino Acid Deletion in a Male Patient With Congenital Heart Defects, Differences of Sex Development, and Diaphragmatic Hernia.Semantic proximity Read ↗

A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.Semantic proximity Read ↗

Mutation screening and association study of the TSSK4 Gene in Chinese infertile men with impaired spermatogenesis.Semantic proximity Read ↗

Analysis of STAG3 variants in Chinese non-obstructive azoospermia patients with germ cell maturation arrest.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.