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Article

Analysis of Fusion Genes by NanoString System: A Role in Lung Cytology?

26 Jan 2018

Abstract excerpt

CONTEXT: - Patients with non-small cell lung cancer harboring ALK receptor tyrosine kinase ( ALK), ROS proto-oncogene 1 ( ROS1), and ret proto-oncogene ( RET) gene rearrangements can benefit from specific kinase inhibitors. Detection of fusion genes is critical for determining the best treatment. Assessing rearrangements in non-small cell lung cancer remains challenging, particularly for lung cytology. OBJECTIVE:...

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PMID: 29372843
DOI: 10.5858/arpa.2017-0135-ra

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