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Article

Detection of ALK fusion transcripts in FFPE lung cancer samples by NanoString technology

26 May 2017

Abstract excerpt

BACKGROUND: ALK-rearranged lung cancers exhibit specific pathologic and clinical features and are responsive to anti-ALK therapies. Therefore, the detection of ALK-rearrangement is fundamental for personalized lung cancer therapy. Recently, new molecular techniques, such as NanoString nCounter, have been developed to detect ALK fusions with more accuracy and sensitivity. METHODS: In the present study, we intended...

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PMID: 28549458
DOI: 10.1186/s12890-017-0428-0

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