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Article

The cytochrome P450 24A1 interaction with adrenodoxin relies on multiple recognition sites that vary among species.

The Journal of biological chemistry - 16 Mar 2018

Estrada D Fernando

Abstract excerpt

Mitochondrial cytochromes P450 (P450s) are responsible for important metabolic reactions, including steps involved in steroid and vitamin D metabolism. The mitochondrial P450 24A1 (CYP24A1) is responsible for deactivation of the bioactive form of vitamin D, 1,25(OH)2D3. Its function relies on formation of a P450-redox partner complex with the ferredoxin and electron donor adrenodoxin (Adx). However, very little...

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Identifiers

PMID: 29371396
DOI: 10.1074/jbc.RA117.001145
PMCID: PMC5857985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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