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Article

Bicaudal D2 is a novel autoantibody target in systemic sclerosis that shares a key epitope with CENP-A but has a distinct clinical phenotype.

Autoimmunity reviews - 1 Mar 2018

Fritzler Marvin J, Hudson Marie, Choi May Y, Mahler Michael, Wang Mianbo, Bentow Chelsea, Milo Jay, Baron Murray

Abstract excerpt

We studied the clinical correlations and epitopes of autoantibodies directed to a novel autoantigen, Bicaudal D (BICD2), in systemic sclerosis (SSc) and reviewed its relationship to centromere protein A (CENP-A). 451 SSc sera were tested for anti-BICD2 using a paramagnetic bead immunoassay and then univariate and multivariate logistic regression was used to study the association between anti-BICD2 and demographic...

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Identifiers

PMID: 29369808
DOI: 10.1016/j.autrev.2018.01.006

Genes

BICD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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