Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

24 Jan 2018

Abstract excerpt

BACKGROUND: Fasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting livestock worldwide, and an emerging food-borne disease in humans. Even when effective treatments are available, drugs are costly and can result in tolerance, liver damage and normally they do not prevent reinfection. Drug-resistant strains in livestock have been reported in various countries and, more worryingly, drug...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Helminth infection and control
Share to Parasites and Host Interactions
Share to Parasitic Diseases Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29368659
DOI: 10.1186/s13071-017-2553-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugsPMID 29368659Read ↗

Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populationsSemantic proximity Read ↗

Independent origins and non-parallel selection signatures of triclabendazole resistance in Fasciola hepatica.Semantic proximity Read ↗

Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and ProteomicsSemantic proximity Read ↗

Different SNPs in Fasciola hepatica P-glycoprotein from diverse Latin American populations are not associated with Triclabendazole resistance.Semantic proximity Read ↗

Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia LinesSemantic proximity Read ↗

Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug ResistanceSemantic proximity Read ↗

Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalisSemantic proximity Read ↗

Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistanceSemantic proximity Read ↗

Differential Gene Expression and Infection Profiles of Cutaneous and Mucosal Leishmania braziliensis Isolates from the Same PatientSemantic proximity Read ↗

An amino acid substitution in Fasciola hepatica P-glycoprotein from triclabendazole-resistant and triclabendazole-susceptible populations.Semantic proximity Read ↗

Transcriptomic analysis of benznidazole-resistant Trypanosoma cruzi clone reveals nitroreductase I-independent resistance mechanismsSemantic proximity Read ↗

Targeted gene expression profiling in Leishmania braziliensis and Leishmania guyanensis parasites isolated from Brazilian patients with different antimonial treatment outcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.