Article
A Perfect Match Genomic Landscape Provides a Unified Framework for the Precise Detection of Variation in Natural and Synthetic Haploid Genomes.
Genetics - 1 Apr 2018
Palacios-Flores Kim, García-Sotelo Jair, Castillo Alejandra, Uribe Carina, Aguilar Luis, Morales Lucía, Gómez-Romero Laura, Reyes José, Garciarubio Alejandro, Boege Margareta, Dávila Guillermo
Abstract excerpt
We present a conceptually simple, sensitive, precise, and essentially nonstatistical solution for the analysis of genome variation in haploid organisms. The generation of a Perfect Match Genomic Landscape (PMGL), which computes intergenome identity with single nucleotide resolution, reveals signatures of variation wherever a query genome differs from a reference genome. Such signatures encode the precise location...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
