Article
Context-dependent individualization of nucleotides and virtual genomic hybridization allow the precise location of human SNPs.
Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 2011
Reyes José, Gómez-Romero Laura, Ibarra-Soria Ximena, Palacios-Flores Kim, Arriola Luis R, Wences Alejandro, García Delfino, Boege Margareta, Dávila Guillermo, Flores Margarita, Palacios Rafael
Abstract excerpt
We have entered the era of individual genomic sequencing, and can already see exponential progress in the field. It is of utmost importance to exclude false-positive variants from reported datasets. However, because of the nature of the used algorithms, this task has not been optimized to the required level of precision. This study presents a unique strategy for identifying SNPs, called COIN-VGH, that largely...
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