Article
Perfect Match Genomic Landscape strategy: Refinement and customization of reference genomes.
Proceedings of the National Academy of Sciences of the United States of America - 6 Apr 2021
Palacios-Flores Kim, García-Sotelo Jair, Castillo Alejandra, Uribe Carina, Morales Lucía, Boege Margareta, Dávila Guillermo, Flores Margarita, Palacios Rafael
Abstract excerpt
When addressing a genomic question, having a reliable and adequate reference genome is of utmost importance. This drives the necessity to refine and customize reference genomes (RGs). Our laboratory has recently developed a strategy, the Perfect Match Genomic Landscape (PMGL), to detect variation between genomes [K. Palacios-Flores et al.Genetics 208, 1631-1641 (2018)]. The PMGL is precise and sensitive and, in...
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