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Article

Genetic differences in C57BL/6 mouse substrains affect kidney crystal deposition.

Urolithiasis - 1 Nov 2018

Usami Masayuki, Okada Atsushi, Taguchi Kazumi, Hamamoto Shuzo, Kohri Kenjiro, Yasui Takahiro

Abstract excerpt

We previously established an experimental model of calcium oxalate crystal deposition in the mouse kidney using C57BL/6 mice. C57BL/6J (B6J) and C57BL/6N (B6N) are two core substrains of C57BL/6 mice. B6J and B6N substrains have approximately the same genomic sequence. However, in whole-genome analyses, substrains have slight genetic differences in some genes. In this study, we used these substrains as kidney...

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PMID: 29362828
DOI: 10.1007/s00240-018-1040-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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