Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mouse model of type B cystinuria due to spontaneous mutation in FVB/NJcl mice.

Urolithiasis - 1 Dec 2022

Sasaki Hayato, Sasaki Takeru, Hiura Koki, Watanabe Masaki, Sasaki Nobuya

Abstract excerpt

Cystinuria is an autosomal metabolic disorder caused by mutations in the SLC3A1 and SLC7A9 genes, encoding the amino acid transporter proteins rBAT and b0,+AT, respectively. Based on the causative gene, cystinuria is classified into 3 types: type A (SLC3A1), type B (SLC7A9), and type AB (SLC3A1 and SLC7A9). Patients with cystinuria exhibit hyperexcretion of cystine and dibasic amino acids in the urine and develop...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Transport Systems, Basic
Share to Amino Acid Transport Systems, Neutral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystine

Share to Cystinuria

Share to Disease Models, Animal

Share to Mutation

Source

Identifiers

PMID: 35988091
DOI: 10.1007/s00240-022-01356-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mouse model of type B cystinuria due to spontaneous mutation in FVB/NJcl mice.PMID 35988091Read ↗

An animal model of type A cystinuria due to spontaneous mutation in 129S2/SvPasCrl mice.Semantic proximity Read ↗

Digenic Inheritance in Cystinuria Mouse Model.Semantic proximity Read ↗

A mouse model for cystinuria type I.Semantic proximity Read ↗

Generation of a novel <i>Slc7a9</i> <sup>G105R</sup> mutant mouse identifies new biomarkers for cystinuriaSemantic proximity Read ↗

Slc7a9-deficient mice develop cystinuria non-I and cystine urolithiasis.Semantic proximity Read ↗

CRISPR/Cas9 engineering of albino cystinuria Type A mice.Semantic proximity Read ↗

Cystinuria: an inborn cause of urolithiasis.Semantic proximity Read ↗

Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosisSemantic proximity Read ↗

Functional analysis of mutations in SLC7A9, and genotype-phenotype correlation in non-Type I cystinuria.Semantic proximity Read ↗

The molecular basis of cystinuria: an update.Semantic proximity Read ↗

Differences in renal cortex transcriptional profiling of wild-type and novel type B cystinuria model rats.Semantic proximity Read ↗

Genetic and clinical characteristics of Japanese cystinuria with exon and exon-intron boundary variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.