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Transcriptomic analysis of primate placentas and novel rhesus trophoblast cell lines informs investigations of human placentation

21 Jun 2021

Abstract excerpt

BACKGROUND: Proper placentation, including trophoblast differentiation and function, is essential for the health and well-being of both the mother and baby throughout pregnancy. Placental abnormalities that occur during the early stages of development are thought to contribute to preeclampsia and other placenta-related pregnancy complications. However, relatively little is known about these stages in humans due...

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PMID: 34154587
DOI: 10.1186/s12915-021-01056-7

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