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Article

mCCDcl1 cells show plasticity consistent with the ability to transition between principal and intercalated cells.

American journal of physiology. Renal physiology - 1 May 2018

Assmus A M, Mansley M K, Mullins L J, Peter A, Mullins J J

Abstract excerpt

The cortical collecting duct of the mammalian kidney plays a critical role in the regulation of body volume, sodium pH, and osmolarity and is composed of two distinct cells types, principal cells and intercalated cells. Each cell type is detectable in the kidney by the localization of specific transport proteins such as aquaporin 2 (Aqp2) and epithelial sodium channel (ENaC) in principal cells and V-ATPase B1 and...

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PMID: 29357433
DOI: 10.1152/ajprenal.00354.2017

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