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Article

sox2 and sox3 cooperate to regulate otic/epibranchial placode induction in zebrafish.

Developmental biology - 1 Mar 2018

Gou Yunzi, Guo Jinbai, Maulding Kirstin, Riley Bruce B

Abstract excerpt

Expression of sox3 is one of the earliest markers of Fgf-dependent otic/epibranchial placode induction. We report here that sox2 is also expressed in the early otic/epibranchial placode in zebrafish. To address functions of sox2 and sox3, we generated knockouts and heat shock-inducible transgenes. Mutant analysis, and low-level misexpression, showed that sox2 and sox3 act redundantly to establish a full...

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Identifiers

PMID: 29355522
DOI: 10.1016/j.ydbio.2018.01.011
PMCID: PMC5818308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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