Article
Absence of HIV-1 Drug Resistance Mutations Supports the Use of Dolutegravir in Uganda.
AIDS research and human retroviruses - 1 May 2018
Ndashimye Emmanuel, Avino Mariano, Kyeyune Fred, Nankya Immaculate, Gibson Richard M, Nabulime Eva, Poon Art F Y, Kityo Cissy, Mugyenyi Peter, Quiñones-Mateu Miguel E, Arts Eric J
Abstract excerpt
To screen for drug resistance and possible treatment with Dolutegravir (DTG) in treatment-naive patients and those experiencing virologic failure during first-, second-, and third-line combined antiretroviral therapy (cART) in Uganda. Samples from 417 patients in Uganda were analyzed for predicted drug resistance upon failing a first- (N = 158), second- (N = 121), or third-line [all 51 involving Raltegravir...
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