Article
High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam.
Scientific reports - 22 Nov 2023
Bwire George M, Aiko Beatrice Godwin, Mosha Idda H, Kilapilo Mary S, Mangara Alli, Kazonda Patrick, Swai Janeth P, Swalehe Omary, Jordan Michael R, Vercauteren Jurgen, Sando David, Temba David, Shao Amani, Mauka Wilhellmuss, Decouttere Catherine, Vandaele Nico, Sangeda Raphael Z, Killewo Japhet, Vandamme Anne-Mieke
Abstract excerpt
To curb HIV infection rate in Tanzania, antiretroviral therapy (ART) has been scaled up since 2006, and in 2019, the country shifted to regimen including dolutegravir as a default first line. We assessed the success of ART and the contribution of HIV drug resistance (HIVDR) to unsuppressed viral loads. Between February and May 2023 a cross-sectional survey with random sampling was conducted in the six clinics in...
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