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Article

Molecular target analysis of stearoyl-CoA desaturase genes of protozoan parasites.

Acta parasitologica - 26 Mar 2018

Lu He, Qin Xin, Zhang Jing, Zhang Shuang, Zhu Yu, Wu Wei Hua

Abstract excerpt

Protozoan parasites can synthesize polyunsaturated fatty acids. They possess stearoyl-CoA desaturase to convert stearate into oleate and linoleate. Stearoyl-CoA desaturase are the key enzymes required for the synthesis of unsaturated fatty acids. It seems attractive to evaluate the possibility of using unsaturated fatty acid biosynthesis pathways as drug targets. In this study, the authors investigate codon usage...

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PMID: 29351064
DOI: 10.1515/ap-2018-0006

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