Article
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region.
Scientific reports - 18 Jan 2018
Khor Seik-Soon, Morino Ryoko, Nakazono Kazuyuki, Kamitsuji Shigeo, Akita Masanori, Kawajiri Maiko, Yamasaki Tatsuya, Kami Azusa, Hoshi Yuria, Tada Asami, Ishikawa Kenichi, Hine Maaya, Kobayashi Miki, Kurume Nami, Kamatani Naoyuki, Tokunaga Katsushi, Johnson Todd A
Abstract excerpt
Food allergy is an increasingly important health problem in the world. Several genome-wide association studies (GWAS) focused on European ancestry samples have identified food allergy-specific loci in the HLA class II region. We conducted GWAS of self-reported reactivity with common foods using the data from 11011 Japanese women and identified shrimp and peach allergy-specific loci in the HLA-DR/DQ gene region...
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