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Article

Genome-wide association study reveals an association between the HLA-DPB1∗02:01:02 allele and wheat-dependent exercise-induced anaphylaxis.

American journal of human genetics - 5 Aug 2021

Fukunaga Koya, Chinuki Yuko, Hamada Yuto, Fukutomi Yuma, Sugiyama Akiko, Kishikawa Reiko, Fukunaga Atsushi, Oda Yoshiko, Ugajin Tsukasa, Yokozeki Hiroo, Harada Naoe, Suehiro Masataka, Hide Michihiro, Nakagawa Yukinobu, Noguchi Emiko, Nakamura Masashi, Matsunaga Kayoko, Yagami Akiko, Morita Eishin, Mushiroda Taisei

Abstract excerpt

Wheat-dependent exercise-induced anaphylaxis (WDEIA) is a life-threatening food allergy triggered by wheat in combination with the second factor such as exercise. The identification of potential genetic risk factors for this allergy might help high-risk individuals before consuming wheat-containing food. We aimed to identify genetic variants associated with WDEIA. A genome-wide association study was conducted in...

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Identifiers

PMID: 34246321
DOI: 10.1016/j.ajhg.2021.06.017
PMCID: PMC8387458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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