Article
CRISPR RNA and anti-CRISPR protein binding to the Xanthomonas albilineans Csy1-Csy2 heterodimer in the type I-F CRISPR-Cas system.
The Journal of biological chemistry - 23 Feb 2018
Hong Suji, Ka Donghyun, Yoon Seo Jeong, Suh Nayoung, Jeong Migyeong, Suh Jeong-Yong, Bae Euiyoung
Abstract excerpt
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide microbial adaptive immunity against bacteriophages. In type I-F CRISPR-Cas systems, multiple Cas proteins (Csy1-4) compose a surveillance complex (Csy complex) with CRISPR RNA (crRNA) for target recognition. Here, we report the biochemical characterization of the Csy1-Csy2 subcomplex from Xanthomonas...
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