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Article

A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly.

ACS infectious diseases - 8 Jun 2018

Nguyen Ylan, Boulton Stephen, McNicholl E Tyler, Akimoto Madoka, Harvey Hanjeong, Aidoo Francisca, Melacini Giuseppe, Burrows Lori L

Abstract excerpt

Type IVa pili (T4aP) are long, thin surface filaments involved in attachment, motility, biofilm formation, and DNA uptake. They are important virulence factors for many bacteria, including Pseudomonas aeruginosa, an opportunistic pathogen and common cause of hospital-acquired infections. Each helical filament contains thousands of monomers of the major pilin subunit, PilA. Each P. aeruginosa strain expresses one...

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PMID: 29342354
DOI: 10.1021/acsinfecdis.7b00229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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