Article
Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus.
Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2012
Garnett James A, Martínez-Santos Verónica I, Saldaña Zeus, Pape Tillmann, Hawthorne William, Chan Jennifer, Simpson Peter J, Cota Ernesto, Puente José L, Girón Jorge A, Matthews Steve
Abstract excerpt
Bacteria have evolved a variety of mechanisms for developing community-based biofilms. These bacterial aggregates are of clinical importance, as they are a major source of recurrent disease. Bacterial surface fibers (pili) permit adherence to biotic and abiotic substrates, often in a highly specific manner. The Escherichia coli common pilus (ECP) represents a remarkable family of extracellular fibers that are...
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