Article
Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution.
Structure (London, England : 1993) - 5 Sept 2017
Wang Fengbin, Coureuil Mathieu, Osinski Tomasz, Orlova Albina, Altindal Tuba, Gesbert Gaël, Nassif Xavier, Egelman Edward H, Craig Lisa
Abstract excerpt
We report here cryoelectron microscopy reconstructions of type IV pili (T4P) from two important human pathogens, Pseudomonas aeruginosa and Neisseria gonorrhoeae, at ∼ 8 and 5 Å resolution, respectively. The two structures reveal distinct arrangements of the pilin globular domains on the pilus surfaces, which impart different helical parameters, but similar packing of the conserved N-terminal α helices, α1, in...
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