Article
Secondary Metabolism and Interspecific Competition Affect Accumulation of Spontaneous Mutants in the GacS-GacA Regulatory System in Pseudomonas protegens.
mBio - 16 Jan 2018
Yan Qing, Lopes Lucas D, Shaffer Brenda T, Kidarsa Teresa A, Vining Oliver, Philmus Benjamin, Song Chunxu, Stockwell Virginia O, Raaijmakers Jos M, McPhail Kerry L, Andreote Fernando D, Chang Jeff H, Loper Joyce E
Abstract excerpt
Secondary metabolites are synthesized by many microorganisms and provide a fitness benefit in the presence of competitors and predators. Secondary metabolism also can be costly, as it shunts energy and intermediates from primary metabolism. In Pseudomonas spp., secondary metabolism is controlled by the GacS-GacA global regulatory system. Intriguingly, spontaneous mutations in gacS or gacA (Gac- mutants) are...
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