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Article

Association between the Intron 8 VNTR Polymorphism of the DAT1 Gene and Crack Cocaine Addiction.

Neuropsychobiology - 1 Jan 2017

Stolf Anderson R, Müller Diana, Schuch Jaqueline B, Akutagava-Martins Gláucia C, Guimaraes Luciano S P, Szobot Claudia M, Halpern Ricardo, Kessler Felix H P, Pechansky Flavio, Roman Tatiana

Abstract excerpt

BACKGROUND: This study aims to compare allele and genotype frequencies of a 30-bp variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene, located at intron 8, between adult crack cocaine users and nonaddicted individuals. Due to its involvement in drug addiction, this gene is a good candidate for molecular studies. METHODS: A cross-sectional sample of 239 current adult crack abusers or dependents...

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PMID: 29332099
DOI: 10.1159/000485128

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