Article
Establishment of TUSMi003-A, an induced pluripotent stem cell (iPSC) line from a 62-year old Chinese Han patient with Alzheimer's disease with ApoE3/4 genetic background.
Stem cell research - 1 Mar 2018
Wang Ying, Yu Hongxiang, Zhang Yue, Zhang Jing, Chen Keni, Sun Heng, Meng Shulin, Li Gang, Lei Ying, Zhao Jian
Abstract excerpt
A 62-year old Chinese Han Alzheimer's disease (AD) female patient with ApoE3/4 genetic background donated her Peripheral blood mononuclear cells (PBMC). The non-integrating episomal vector system was used to reprogrammed PBMCs with the human OKSM transcription factors. The pluripotency of transgene-free iPSCs was confirmed by immunocytochemistry for pluripotency markers and by the ability of the iPSCs to...
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