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Article

Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo

1 Jan 2018

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29324226
DOI: 10.1016/j.chom.2017.12.009

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Related research

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Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In VivoPMID 29324226Read ↗

Lack of adaptation to human tetherin in HIV-1 Group O and PSemantic proximity Read ↗

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain VariantsSemantic proximity Read ↗

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals.Semantic proximity Read ↗

Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.Semantic proximity Read ↗

Human Tetherin Exerts Strong Selection Pressure on the HIV-1 Group N Vpu ProteinSemantic proximity Read ↗

Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestrationSemantic proximity Read ↗

Determinants of Tetherin Antagonism in the Transmembrane Domain of the Human Immunodeficiency Virus Type 1 Vpu ProteinSemantic proximity Read ↗

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Structural basis of tetherin function.Semantic proximity Read ↗

Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic ApproachesSemantic proximity Read ↗

Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceSemantic proximity Read ↗

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