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Article

Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans.

Scientific reports - 11 Jan 2018

Cho Yoonsu, Kwak Soyoung, Lewis Sarah J, Wade Kaitlin H, Relton Caroline L, Smith George Davey, Shin Min-Jeong

Abstract excerpt

Previous studies have indicated an association of higher alcohol intake with cardiovascular disease and related traits, but causation has not been definitively established. In this study, the causal effect of alcohol intake on hypertension in 2,011 men and women from the Ansan-Ansung cohort was estimated using an instrumental variable (IV) approach, with both a phenotypic and genotypic instrument for alcohol...

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Share to Aged
Share to Alcohol Drinking
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flushing

Share to Hypertension

Share to Polymorphism, Single Nucleotide

Share to Republic of Korea

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Source

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Identifiers

PMID: 29323248
DOI: 10.1038/s41598-017-18856-z
PMCID: PMC5765011

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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