Article
Moderate alcohol use and cardiovascular disease from Mendelian randomization.
PloS one - 1 Jan 2013
Au Yeung Shiu Lun, Jiang Chaoqiang, Cheng Kar Keung, Cowling Benjamin J, Liu Bin, Zhang Weisen, Lam Tai Hing, Leung Gabriel M, Schooling C Mary
Abstract excerpt
BACKGROUND: Observational studies show moderate alcohol use negatively associated with ischemic heart disease (IHD) and cardiovascular disease (CVD). However, healthier attributes among moderate users compared to never users may confound the apparent association. A potentially less biased way to examine the association is Mendelian randomization, using alcohol metabolizing genes which influence alcohol use....
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