Article
Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study.
Scientific reports - 21 Dec 2015
Cho Yoonsu, Shin So-Youn, Won Sungho, Relton Caroline L, Davey Smith George, Shin Min-Jeong
Abstract excerpt
Mendelian randomisation studies from Asia suggest detrimental influences of alcohol on cardiovascular risk factors, but such associations are observed mainly in men. The absence of associations of genetic variants (e.g. rs671 in ALDH2) with such risk factors in women - who drank little in these populations - provides evidence that the observations are not due to genetic pleiotropy. Here, we present a Mendelian...
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