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Article

Array-based DNA methylation profiling in male infertility reveals allele-specific DNA methylation in PIWIL1 and PIWIL2.

Fertility and sterility - 1 Apr 2014

Friemel Carolin, Ammerpohl Ole, Gutwein Jana, Schmutzler Andreas G, Caliebe Almuth, Kautza Monika, von Otte Sören, Siebert Reiner, Bens Susanne

Abstract excerpt

OBJECTIVE: To identify CpG sites differentially methylated in peripheral blood of men with idiopathic infertility due to impaired spermatogenesis as compared with fertile controls. DESIGN: DNA methylation profiling on peripheral blood samples using the HumanMethylation450 BeadChip (Illumina) in patients and controls, single-nucleotide polymorphism (SNP) typing by Sanger sequencing. SETTING: University institute...

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Source

Identifiers

PMID: 24524831
DOI: 10.1016/j.fertnstert.2013.12.054

Genes

PIWIL1
PIWIL2
BRSK2
CFTR
ENO1
LBX2
MTA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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