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Article

The Association Between Variants of Receptor for Advanced Glycation End Products (RAGE) Gene Polymorphisms and Age-Related Macular Degeneration.

Medical science monitor : international medical journal of experimental and clinical research - 10 Jan 2018

Banevicius Mantas, Vilkeviciute Alvita, Kriauciuniene Loresa, Liutkeviciene Rasa, Deltuva Vytenis Pranas

Abstract excerpt

BACKGROUND Age-related macular degeneration (AMD) is the leading cause of blindness in people aged 65 years and older in developed countries. The pathogenesis of AMD has been linked to mechanisms involving inflammation, oxidative stress, and basal laminar deposit formation between retinal pigment epithelium (RPE) cells and the basal membrane, caused by advanced glycation end products (AGEs). AGEs are implicated...

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Identifiers

PMID: 29317590
DOI: 10.12659/msm.905311
PMCID: PMC5771184

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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