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Article

A functional link between NAD+ homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae.

The Journal of biological chemistry - 23 Feb 2018

Croft Trevor, James Theoga Raj Christol, Salemi Michelle, Phinney Brett S, Lin Su-Ju

Abstract excerpt

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite participating in cellular redox chemistry and signaling, and the complex regulation of NAD+ metabolism is not yet fully understood. To investigate this, we established a NAD+-intermediate specific reporter system to identify factors required for salvage of metabolically linked nicotinamide (NAM) and nicotinic acid (NA). Mutants lacking components...

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Identifiers

PMID: 29317496
DOI: 10.1074/jbc.M117.807214
PMCID: PMC5827443

Genes

TPM1
ATG14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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