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Article

Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex.

PLoS neglected tropical diseases - 1 Sept 2020

Salloum Tamara, Moussa Rim, Rahy Ryan, Al Deek Jospin, Khalifeh Ibrahim, El Hajj Rana, Hall Neil, Hirt Robert P, Tokajian Sima

Abstract excerpt

Leishmania tropica is one of the main causative agents of cutaneous leishmaniasis (CL). Population structures of L. tropica appear to be genetically highly diverse. However, the relationship between L. tropica strains genomic diversity, protein coding gene evolution and biogeography are still poorly understood. In this study, we sequenced the genomes of three new clinical L. tropica isolates, two derived from a...

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Identifiers

PMID: 32946436
DOI: 10.1371/journal.pntd.0008684
PMCID: PMC7526921

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