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Article

Development and Characterization of a Novel Congenic Rat Strain for Obesity and Cancer Research.

Nutrition and cancer - 1 Jan 2000

O'Neill Ann Marie, Gillaspie Erin A, Burrington Christine M, Lynch Darin T, Dauchy Robert T, Blask David E, Tirrell Paul C, Reis Brian A, Horsman Melissa J, Greene Michael W

Abstract excerpt

The association between a Western Diet and colon cancer suggests that dietary factors and/or obesity may contribute to cancer progression. Our objective was to develop a new animal model of obesity and the associated pathophysiology to investigate human cancer independent of dietary components that induce obesity. A novel congenic rat strain was established by introducing the fa allele from the Zucker rat into...

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Identifiers

PMID: 29313726
DOI: 10.1080/01635581.2018.1412483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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