Article

Modeling the effects of genetic and diet induced obesity on melanoma progression in zebrafish

2022-05-29

Abstract excerpt

Obesity is a rising concern and associated with an increase in numerous cancers often in a sex-specific manner. Preclinical models are needed to deconvolute the intersection between obesity, sex, and cancer. We have generated a zebrafish system that can be used as a platform for studying these factors. We studied how germline overexpression of AgRP along with a high-fat diet (HFD) affects melanomas dependent on BR...

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Literature Corpus work: 0a8938dd-ef34-522a-9511-0cc2e53e76fb
DOI: 10.1101/2022.05.27.493792

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