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Article

The Drift in Molecular Testing for Influenza: Mutations Affecting Assay Performance.

Journal of clinical microbiology - 1 Mar 2018

Stellrecht Kathleen A

Abstract excerpt

Influenza is associated with rapid evolution due to lack of RNA polymerase proofreading, immunogenic selection, and frequent rearrangement of gene segments. Evolutionary changes affecting the performance of diagnostic testing have long been recognized. Hence, it is not surprising that such challenges apply to nucleic acid amplification tests, even though they are designed to target highly conserved regions....

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Identifiers

PMID: 29305549
DOI: 10.1128/JCM.01531-17
PMCID: PMC5824055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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