Article
History of matrix genes mutations within PCR target regions among circulating influenza H3N2 clades over ten-plus-years.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2018
Stellrecht Kathleen A
Abstract excerpt
BACKGROUND: Emerging influenza A/H3N2 clades have been associated with M1 gene mutations which affect the performance of commercial PCR assays. OBJECTIVES AND STUDY DESIGN: The evolution and prevalence of problematic M1 mutations, and their associated viral clades, were investigated. All European and USA isolates from the GISAID database with both HA and M1 sequences available, collected during the respiratory...
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